The Scythe was originally wielded by Death, who used it against Dante during their battle in Acre. Dante manages to take the scythe from Death, using it to slay its former master. He subsequently discards his halberd in favour of the new weapon, using it throughout his battles in Hell.
After defeating Lucifer at the end of the game, the scythe disintegrates.
Main article: Unholy Abilities
Death's Scythe is able to shift its form in a variety of ways, growing and shrinking as needed to grab, slash, and impale objects or enemies. It can change into a straight, spear-like form, extend into a hooked chain, or collapse into a blade attached to Dante's arm.
Dante uses souls to upgrade the scythe, which grows stronger by absorbing Unholy power. Each time Dante chooses to condemn souls or demons, Unholy Experience is generated - once enough experience is gained, the scythe becomes stronger and gains new abilities. The scythe also has the power to take mana from slain creatures, once the required ability is unlocked.
- In Dante's Inferno: An Animated Epic, the scythe is a regular weapon wielded by demons and not the weapon of Death. Plus, Dante still has it by the end of the movie.
- The name of the unholy move "Diabolic Guillotine" is an slight ananchronism; The guillotine, an execution device, was invented around 1789. However, this could be explained by the fact that the afterlife is considered to be outside of time.
- The overall moveset of the Scythe is more akin to those of God of War series where attacks orbit in a fluid streak of combo with interchangable input of Light and Heavy attacks with slight variation between pressing or holding buttons accompanied with some special moves that requires an extra simultaneous input ; In contrast to those like Devil May Cry series where stand-alone attack moves are used in sequence tentatively, with each of them requiring specific input that most of the time also require correct alignments of the joystick and sometimes, different pacing of button press.